EQUIBIOS
E Q U I B I O S i s :
Equibios is a yeast blend to help maintain normal gastrointestinal health in the horse, containing Sacchromyces boulardii and brewer’s dried yeast (MOS).
An effective way to stop pathogens from causing gastrointestinal upset is to obstruct their attachment to the epithelial cells in the gut. The ingredients in Equibios have “sticky, sugar-like” properties that assist in this process, thus helping to maintain normal G.I. function.
There are several products on the market today that contain bacterial organisms to assist with normal G.I. function of the horse. Equibios does not contain any bacterial organisms, but does contain yeast organisms. These organisms were chosen over bacterial organisms because of the numerous studies supporting the use of live yeast and yeast wall extract in horses and other species.
Studies show that S. boulardii is a live yeast that binds the surface of pathogens such as Clostridium and Salmonella1, inhibits Clostridial toxins2 has a positive effect on the immune system3. Studies also show that Brewer’s dried yeast (MOS) are yeast wall extracts that bind to the surface of Salmonella and other bacteria4.
1Gedek, 1999, 2Buts et al, 1990 and Caetano et al, 1986, 3Castagliuolo, 1999, 4Corliss, 2003
E Q U I B I O S s h o u l d b e u s e d :
• During periods of abnormal G.I. Function
• Before and during treatment with antibiotics
• Before and during periods of stress
• Before and during periods of hospitalization
• Prior to shipping
• Prior to a stressful performance
• Weaning
• Maintaining normal G.I. function
E Q U I B I O S
Feeding Directions:
Loading Level: For an adult horse, feed 1.5 tablespoons twice daily for 2 weeks either as a top dress to the feed or place into the mouth directly on the tongue. For a foal, mix 0.5 teaspoon per 100 pounds of body weight with water and dispense orally twice daily for 2 weeks.
For maintenance: For an adult horse, feed 1.5 tablespoons once daily either as a top dress to the feed or place into the mouth directly on the tongue. For a foal, mix 0.5 teaspoon per 100 pounds of body weight with water and dispense orally once daily.
Supporting literature for Equibios:
Efficacy of Saccharomyces boulardii for treatment of horses with
acute enterocolitis, Desrochers et al, 2005
Saccharomyces boulardii for Clostridium difficile-Associate
Enteropathies in Infants, Jean Paul Buts et al, 1993
Adherence of Escherichia coli serogroup 0 157 and the Salmonella
Typhimurium mutant DT 104 to the surface of Saccharomyces
boulardii, Gedek, 1999
A Randomized Placebo-Controlled Trial of Saccharomyces bourlardii in Combination With Standard Antibiotics for Clostridium difficile Disease, McFarland et al, 1994
Five Application for mannan oligosaccharides in ruminants and
pre-ruminants, Corless, 2003
Saccharomyces boulardii Protease Inhibits the Effects of Clostridium difficile Toxins A and B in Human Colonic Mucosa, Castagliuolo et al, 1999
Prevention of Antibiotic-Associated Diarrhea by Saccharomyces
boulardi: A Prospective Study, Surawicz et al, 1989
Prevention of β-Lactam-Associated Diarrhea by Saccharomyces
boulardii Compared with Placebo, McFarland et al, 1995
Effect of Yeast-Supplemented Feed on Salmonella and Campylobacter Populations in Broilers, Line et al, 1998
Yeast Treatment to Reduce Salmonella and Campylobacter Populations Associated with Broiler Chickens Subjected to
Transport Stress, Line et al, 1997
Stimulation of Secretory IgA and Secretory Component of Immunoglobulins in Small Intestine of Rats Treated with Saccharomyces boulardii, Buts et al, 1990
Prevention of Further Recurrences of Clostridium difficile Colitis
with Saccharomyces boulardii, Kimmey et al, 1990
Saccharomyces boulardii prevents diarrhea in critically ill tube-fed
patients, Bleichner et al, 1997
Immunopharmacological Effects of Saccharomyces boulardii in
Healthy Human Volunteers, Caetano et al, 1986